Exosomes
Regenerative nano-vesicles derived from stem cells.
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Stem cells, exosomes and PRP treatments by ISSCA-certified physician at Edificio Forum, El Poblado
Regenerative medicine with stem cells is the most exciting frontier of modern aesthetic medicine. At Dr. Catalina Henao Grajales' clinic at Edificio Forum, Medellín, Colombia, we offer advanced treatments with stem cells, derived exosomes and autologous platelet-rich plasma (PRP) — all backed by the international ISSCA certification in Point of Care Regenerative Medicine (registration #8792, October 2025).
Stem cells are undifferentiated cells with the unique ability to self-renew and differentiate into different cell types. In aesthetic medicine we use mesenchymal stem cells and their derivatives (exosomes, growth factors) to stimulate natural tissue regeneration.
Deep facial rejuvenation, skin quality improvement, scar treatment, hair loss (alopecia), comprehensive anti-aging and, in medical applications, joint pain and tendinitis.
Results are progressive: visible from weeks 2-3, peak at 4-6 months. Total duration: 12-24 months depending on protocol.
Dr. Catalina Henao Grajales, Universidad CES medical doctor with ISSCA Regenerative Medicine certification. 15+ years in aesthetic medicine. Personally performs every procedure.
Yes, when performed with certified medical-grade products, in an equipped medical office and by a physician with specific training. We work only with derivatives from certified product lines with complete documentation.
Stem cells are the master cells of the human body. Unlike differentiated cells (which already have a specific function like skin, muscle or nerve cells), stem cells retain two exceptional properties:
This duality is the basis of their regenerative power. When introduced into damaged or aged tissue, stem cells can repair, replace and regenerate that tissue from its most fundamental level — the cellular.
The most used adult stem cells in regenerative aesthetic medicine. Obtained from adipose tissue (fat), bone marrow or certified donor umbilical cord. They have immunomodulatory potency (reduce inflammation) and ability to differentiate into connective tissue cells: skin, cartilage, bone. Excellent safety profile documented in thousands of clinical studies.
Exosomes are extracellular nano-vesicles of 30 to 150 nanometers that stem cells release as chemical messengers. They contain all the "regenerative information" of the stem cell (growth factors, microRNA, proteins) without the cells themselves. They have unique advantages: no critical refrigeration required, they are acellular (no immunological risk) and cross tissue barriers more easily.
PRP is not technically stem cells, but it is one of the pillars of regenerative medicine. Obtained from your own blood (autologous, zero rejection risk) and concentrated to release platelets rich in growth factors (PDGF, TGF-β, VEGF, EGF). Often combined with stem cells or exosomes to enhance results.
More than a superficial treatment, stem cells and exosomes act in the deep dermal plane, stimulating endogenous production of type I and III collagen, improving elastin and increasing the extracellular matrix. Result: firmer, thicker, hydrated skin with better overall quality. Ideal for patients with first signs of aging (35+ years) or as intensive maintenance.
Deep atrophic acne scars (boxcar, ice pick) and traumatic scars that don't respond well to microneedling alone often improve when combined with exosomes applied through Dermapen. Exosomes activate scar fibroblasts and promote tissue remodeling.
Scalp application of exosomes combined with PRP stimulates miniaturizing hair follicles (early stage baldness). One of the most effective non-pharmacological treatments for early androgenetic alopecia in men and women. Protocol: 4-6 sessions every 3-4 weeks, then maintenance.
For patients who want not just to "look better" but to age better, stem cell anti-aging protocols act at systemic level improving: skin and hair quality, energy, post-exercise recovery, immune function and overall wellness. Requires full prior medical assessment.
Intra-articular PRP, exosome or stem cell injections in knees, shoulders, elbows or tendons can accelerate healing of tendinitis, mild to moderate arthritis and sports injuries. Often combined with physiotherapy for better recovery.
| Phase | What it includes | Duration |
|---|---|---|
| 1. Assessment | Complete medical history, physical exam, lab analysis as indicated. Contraindication screening. | 45-60 min |
| 2. Protocol design | Define treatment type (stem cells, exosomes, PRP or combinations), zones, sessions and schedule. | 20-30 min |
| 3. Application | Outpatient medical procedure. Time varies by protocol: facial 45-60 min, hair 30-45 min, joint 20-30 min. | 30-90 min/session |
| 4. Follow-up | Check-up at 2 weeks, month 1, month 3 and 6. Direct WhatsApp follow-up with the doctor. | 6 months |
| Feature | Stem cells | Exosomes | PRP |
|---|---|---|---|
| What are they? | Living undifferentiated cells | Nano-vesicles (30-150 nm) | Concentrated platelets from your own blood |
| Origin | Certified donor | Controlled stem cell culture | Your own blood (autologous) |
| Regenerative potency | Maximum | High | Moderate-high |
| Immunological risk | Low | Zero | Zero (autologous) |
| Relative cost | High | Medium-high | Medium |
| Protocol | Sessions | Interval |
|---|---|---|
| Facial rejuvenation with exosomes | 3-4 sessions | Every 4 weeks |
| Hair (androgenetic alopecia) | 4-6 sessions | Every 3-4 weeks |
| Facial PRP | 3-4 sessions | Monthly |
| Acne scars (Dermapen + exosomes) | 4-6 sessions | Monthly |
| Joint (knee/shoulder) | 1-3 sessions | As needed |
| Comprehensive anti-aging | Personalized | Personalized |
Personalized consultation with Dr. Catalina Henao, ISSCA certified #8792, at Edificio Forum, El Poblado, Medellín, Colombia.
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